NFL odds, lines, picks, predictions for Week 4, 2020: Proven model backing Cowboys, 49ers

There could be several tight games in Week 4 according to the latest NFL odds from William Hill. Three of Sunday’s games carry NFL spreads of a field goal or less, including the Indianapolis Colts as 2.5-point road favorites over the undefeated Chicago Bears. The winless Cincinnati Bengals are a favored by a field goal over the Jacksonville Jaguars in the latest NFL Vegas lines, while the unbeaten Buffalo Bills are also favored by three over the Las Vegas Raiders.

Are the Colts, Bengals, and Bills attractive favorites for your NFL Vegas picks, even with Buffalo and Indianapolis on the road? And which Week 4 matchups provide the best value for Week 4 NFL bets? All of the Week 4 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best Week 4 NFL picks now.

The SportsLine Projection Model simulates every NFL game 10,000 times and is up over $7,500 for $100 players on its top-rated NFL picks since its inception five years ago.

It’s off to a strong 7-2 roll on top-rated NFL picks this season. The model enters Week 4 on an incredible 103-67 roll on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, it has examined the latest Week 4 NFL odds and NFL betting lines, simulated every snap, and its predictions are in. Head to SportsLine now to see them all.

Top NFL predictions for Week 4

One of the top Week 4 NFL predictions the model recommends: The Cowboys (-4.5) cover at home against the Browns. Dallas is off to a disappointing 1-2 straight-up start with an 0-3 mark against the spread. That’s the worst start against the spread for the Cowboys since 1989, when they began 0-6. 

But Cleveland has struggled mightily against the spread on the road, entering this matchup on an 0-7 ATS losing streak away from FirstEnergy Stadium. SportsLine’s model is calling for more big offensive numbers from Dallas, as quarterback Dak Prescott throws for well over 300 yards and running back Ezekiel Elliott easily clears 100 yards of total offense. Dallas covers almost 60 percent of the time, while the under (55.5) hits in well over 50 percent of simulations. 

Another one of the top Week 4 NFL picks from the model: The San Francisco 49ers (-7) cover as home favorites against the Philadelphia Eagles on Sunday Night Football. San Francisco is 2-1, having defeated the New York Giants and New York Jets following a season-opening loss to the Arizona Cardinals. The 49ers have been riddled with injuries, but will likely get tight end George Kittle (knee) and wide receiver Deebo Samuel (foot) back from injury.

The Eagles are 0-2-1, having tied the Bengals last Sunday. Quarterback Carson Wentz has thrown for 737 yards in three games, but he has also thrown twice as many interceptions (six) as he has touchdowns (three). SportsLine’s model projects that Wentz will struggle against San Francisco’s defense, throwing for just over 200 yards and one touchdown with an interception. The model also says the Niners cover in well over 50 percent of simulations. The over (45) also hits well over 50 percent of the time. 

How to make Week 4 NFL picks 

The model also has made the call on the huge Chiefs vs. Patriots matchup as well as every other game on the Week 4 NFL schedule. It’s also identified a Super Bowl contender that goes down hard. You can only get every pick for every game at SportsLine.

What NFL picks can you make with confidence in Week 4? And which Super Bowl contender goes down hard? Check out the latest NFL odds from William Hill below and then visit SportsLine to see which NFL teams are winning more than 50 percent of simulations, all from the model that is up over $7,500 on its top-rated NFL picks. 

NFL odds, matchups for Week 4

Indianapolis Colts at Chicago Bears (+2.5, 43.5)
New Orleans Saints at Detroit Lions (+4, 54)
Arizona Cardinals at Carolina Panthers (+3.5, 51)
Jacksonville Jaguars at Cincinnati Bengals (-3, 49)
Cleveland Browns at Dallas Cowboys (-4.5, 56)
Minnesota Vikings at Houston Texans (-4.5, 54.5)
Seattle Seahawks at Miami Dolphins (+6.5, 53)
Los Angeles Chargers at Tampa Bay Buccaneers (-7, 43)
Pittsburgh Steelers at Tennessee Titans (off the board)
New York Giants at Los Angeles Rams (-13, 48)
Buffalo Bills at Las Vegas Raiders (+3, 52.5)
Philadelphia Eagles at San Francisco 49ers (-7, 46)
Baltimore Ravens at Washington Football Team (+13, 45)
New England Patriots at Kansas City Chiefs (-7, 53)
Atlanta Falcons at Green Bay Packers (-7.5, 56.5)

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