Cincinnati vs. South Florida odds, line: 2020 college football picks, Week 5 predictions from advanced model

The Cincinnati Bearcats and the South Florida Bulls will face off in an American Athletic clash at 3:30 p.m. ET on Saturday at Nippert Stadium. Cincinnati is 2-0 on the season, while South Florida is 1-1. The series began in 2003 and the two programs have met every season since with the Bearcats holding a 10-7 lead after winning each of the last two meetings.

However, the Bulls have covered in each of the last five games the two teams have played. This time around, the Bearcats are favored by 22-points in the latest Cincinnati vs. South Florida odds from William Hill, while the over-under is set at 46. Before entering any South Florida vs. Cincinnati picks, you’ll want to see the college football predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the

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